Hi Everyone. Are there any wegeners people who get their PR3 antibody tested
http://www.arupconsult.com/Topics/ANCA.html#tabs=0 This page gives some info about PR3 - apparently it is part of the ANCA test
Pr3 is for us weggies. I am tested several times each year, as a part of my rituximab treatments. Our test scale here is different, the number for "normal" people is under 2.0. When I had a bad flare it was 14. (The flare was caught early.) Now I've been under 1.0 for some time, and there's no WG activity that I can notice.
"Overall, low predictive values for relapse were found, so it's not justified to escalate immunosuppresive therapy solely on the basis of an increase in ANCA level, as determined by PR3/MPO ELISA. An increase should be taken as a warning and the patient observed more closely." - Vasculitis In Clinical Practice, page 67
I had a PR3 level 0f 100 about 18 months ago and now my PR3 level is 9. According to my UK consultant it should be below 5 for the normal range but he isn't as worried about it being 9 because it's been 100 previously